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A: Review articles emphasize optimizing selective NNMT inhibitors like 5Amino1MQ and exploring coadministration with NAD precursors for cardiometabolic disorders

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15 , e108

By inhibiting NNMT, 5-Amino-1MQ prevents this NAD drain , allowing cells to maintain higher NAD availability

Peripherally, pancytopenia is most often observed, but only 1-2 of the major cell types (erythrocytes, leukocytes, platelets) may be depressed in some cases

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