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Ann N Y Acad Sci 1031:249262

5-azacytidine) might have a role in the treatment of breast cancer cells with epigenetically silenced CDO1for example, by inducing sensitisation to anthracycline

Both residues are within an ideal hydrogen bond distance from the N-atom of the -amino group of PMP after the formation of the Schiff-base linkage between K274 (K314 of the precursor protein) and PLP (the N-atom of the bound PMP/PLP)