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311 , H1431H1436 (2016)

Risk factors for linezolid-associated thrombocytopenia and negative effect of carbapenem combination

Effects of N-acetylcysteine, oral glutathione and a novel sublingual form of GSH on oxidative stress markers

In a randomized clinical trial on patients with diabetic nephropathy accompanying chronic kidney disease, following NSO treatment, there was a significant reduction in blood glucose, serum creatinine, blood urea, and 24 h total urinary protein levels and an increase in glomerular filtration rate, 24 h total urinary volume, and hemoglobin level [140]

doi:10.1016/j.ejphar.2021.174253 245

This suggests that Nrf2 may mediate expression of BDNF in cells comprising the vasculature and microglia to elevate the expression of antioxidant enzymes