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So, we investigated the active rice D-LDH member for its abiotic stress inducibility

Domingues-FariaCChanetASallesJBerryAGiraudetCPatracVet al

Effect of multiple stresses on germination and growth of D-LDH mutant and OsD-LDH2 transgenic plants The Arabidopsis thaliana seeds of mutant (M), wildtype (WT) and OsD-LDH2 overexpressing transgenic plants (D2TG) were sown on half strength MS agar plates supplemented with different concentrations of various stresses such as D-lactate (010 mM), Methylglyoxal (01 mM), NaCl (0150 mM), Mannitol (0150 mM) and H 2 O 2 (05 mM)

Thirdly, and potentially closely related to the glutamatergic hypothesis, is the theory of oxidative stress [8]

Since an exogenous antioxidant exhibits anticancer effect by both antioxidant (chemopreventive) and prooxidant (chemotherapeutic) mechanisms, the dose is a critical factor

We need more targeted studies on low-dose and microdose effects, but the clinical signals are encouraging