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Second, in vivo carcinogenesis studies, such as 18-month chronic inhalation studies, can be conducted in A/J mice to compare the effects of cMRTP aerosol and cigarette smoke on lung tumor incidence and multiplicity

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The Swedish experience may not therefore be generalizable, and it would be premature to use it as a basis for public health recommendations," it said

Smoking marijuana with greater frequency can still increase the risks of stroke or heart disease

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The IARC monographs, referencing studies which used various methods of smoke inhalation, concluded that a significantly greater number of pulmonary tumors occurred among mice exposed to smoke than those in the control groups