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Cancer-derived exosomes as a delivery platform of CRISPR/Cas9 confer cancer cell tropism-dependent targeting

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Straus DS, Pascual G, Li M et al (2002) 15-Deoxy-Delta 12,14-prostaglandin J2 inhibits multiple steps in the NF-kappa B signaling pathway

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In mitochondria, THF is imported via a mitochondrial folate transporter and converted into 5,10-methylene-THF by serine hydroxymethyltransferase 2 (SHMT2), which oxidizes serine to glycine while transferring a one-carbon unit to THF [15]

Once damaged, alveolar epithelial cells are able to secrete the cytokines IL-6, TNF-, and various chemokines such as CXCL1 and CXCL2 to alter the inflammatory cells [34, 35]