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Most studies are of short duration, such as the three-week crossover study in healthy adults [12] or the 12-week modified Atkins intervention in drug-resistant epilepsy [42], and usually refer to small, specific populations

Liu M, Mao G, Zhou X, Wan X, Zhang F, Dai L, Chen Y, Dai N, Zhang Y, Du Q

Dec 2002;7(6):512-22

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In addition to its role in maintaining a normal sleep-wake cycle, melatonin plays an important part in autonomic regulation, including blood pressure, pulse, and temperature, as well as immune response and glucose homeostasis

Deviations in thyroid hormone levels have an implication on the gut microbiotas richness and composition, which is crucial for alterations in thyroid function as represented in the Fig