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Further modifications, including solubility-enhancing groups, led to UAMC-3203, which demonstrated superior potency, stability, and solubility, with no toxicity in mouse models (Devisscher et al., 2018)

A preliminary investigation of nutritional intake and supplement use in Australians with myalgic encephalomyelitis/chronic fatigue syndrome and the implications on health-related quality of life

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Some types of inhibitors directly affect HIF-1 or HIF-2 mRNA or protein level, subunit and subunits dimerization, or the interaction of HIF and the co-activators