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MSC-EVs function predominantly by the activation of autophagy via the catalase enzyme, the Nrf2 signalling pathway, the miR 146a-inhibited NF-B pathway, and the targeting of the PTEN-PI3 K/Akt pathway by miR-223 (145)

Research on rat models documents measurable reductions in pro-inflammatory cytokines (TNF-alpha and IL-6) following BPC-157 administration, limiting excessive tissue damage during recovery

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Inflammatory bowel disease and mutations affecting the interleukin-10 receptor

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E., Chung, R