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Several promising directions are emerging for next-generation research: These approaches may significantly expand the applicability of agar-based nanoparticles in neurological disease therapy and brain-targeted drug delivery

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The gutbrain axis is also inseparable from the HPA axis, a crucial signaling cascade system

Extracellular cysteine can also directly be taken up by cultured astrocytes and used for GSH synthesis, but its disulfide cystine, that is transported into rat astrocytes mainly by the cystineglutamate antiporter X C , serves as the preferred extracellular substrate for the cytosolic cysteine needed for astrocytic GSH synthesis (Kranich et al

doi: 10.1189/jlb.0413240 134 ArizaMECoxBMartinezBMena-PalomoIZarateGJWilliamsMV

Therefore, we examined the effects of GHK-Cu on LPS-induced ROS production and SOD activity in RAW 264.7 cells