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Therapies that rely on scaffold-free cellular approaches, such as ACI, are not designed to handle these mechanical burdens early post-surgery, and thus, utilizing scaffolds with improved bulk mechanical properties could increase efficacy of treatment and promote earlier return to normal activity in these knees

After two years (120 weeks), the patients retained roughly one-third of their original weight loss (5.6% of the original 17.3% loss)

Detailed information on neuropsychological assessment and exclusion criteria have been thoroughly documented in previous publications based on this cohort study 4,20

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