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Markers of oxidative stress and antioxidant status in the plasma, urine and saliva of healthy mice

Incidence has been reported in more than 110 countries, and approximately 1.6 billion individuals are considered at risk, underscoring their status as a recognized international public health concern [13]

Smadbeck J, Peterson MB, Zee BM, Garapaty S, Mago A, Lee C, et al

Other drugs that are highly extracted by the liver include morphine (see above), isoniazid, propranolol, and several tricyclic antidepressants ( Table 31 )