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A beta-mediated ROS production by Cu ions: structural insights, mechanisms and relevance to Alzheimers disease

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ERK5-CHAMP significantly reduced tumor cell growth in vitro and in mouse xenograft tumor models, and preferentially accumulated in tumors relative to levels in normal tissues

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These therapies have a narrow therapeutic window, indicating that their efficacy and toxicity are critically dose dependent

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Springer Nature Singapore, pp 143172

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