glutathione in ovarian cancer a double-edged sword

glutathione in ovarian cancer a double-edged sword Targeting ferroptosis cancer: Novel strategies to overcome chemotherapy resistance Frontiers | Ferroptosis: a dual-edged

Name: glutathione in ovarian cancer a double-edged sword Targeting ferroptosis cancer: Novel strategies to overcome chemotherapy resistance Frontiers | Ferroptosis: a dual-edged
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Frontiers Ferroptosis: a dual edged sword in tumour growth Redox Regulated Iron Metabolism and Ferroptosis in Ovarian Cancer: Molecular Insights and Therapeutic Opportunities Impact of the glutathione synthesis pathway on sulfasalazine treated endometrial cancer Oncotarget Cysteine metabolic circuitries: druggable targets in cancer British Journal of Cancer Frontiers Targeting ferroptosis: a promising avenue for ovarian cancer treatment N Acetyl Cysteine as a promising therapeutic approach in ovarian cancer: potential and perspectives PMC

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doi:10.1016/j.arr.2022.101766

Firstly, we verified across a panel of normal and cancer cell lines with differing p53 status (Supplementary Table 1) that treatment with a lethal dose of APR-246 resulted in higher intracellular ROS (Fig