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Monitoring Protocol: Although the trials showed no concerning laboratory changes, prudent clinical practice suggests baseline and periodic monitoring of metabolic parameters, complete blood counts, liver function, and kidney function

Red or purple chromaturia is a side effect of hydroxocobalamin, typically resolving over several weeks.2 Additional causes of red urine include blood (e.g., traumatic catheterization, malignancy, infection), dietary ingestion (e.g., beets), and medications (e.g., rifampin, phenothiazines).3 Although benign and not warranting further evaluation by itself, hydroxocobalamin-induced discolouration of body fluids may interfere with colorimetric sensors

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4,5 Trigeminal Neuralgia Treatment First-line pharmacologic treatment for TN typically includes anticonvulsant medications, such as carbamazepine, oxcarbazepine, lamotrigine, gabapentin, lacosamide, or the muscle relaxant baclofen