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Table 3: Laboratory Abnormalities Worsened from Baseline in 20% of Patients in KEYNOTE-189 Initial Treatment in Combination with Cisplatin The safety of pemetrexed for injection was evaluated in Study JMDB, a randomized (1:1), open-label, multicenter trial conducted in chemotherapy-naive patients with locally advanced or metastatic NSCLC

A similar work on TD-DCS 46 where they used another breathing exercisebreath holdalso reports a higher changes in the early gate rBFI compared to the late gate

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The most rigorous published study is a double-blind, matched-pairs, parallel-groups trial by Bes et al