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Conclusion This finding suggests that the synergistic effect of genetic factors such as Kcnq1 gene mutations and environmental factors such as obesity and overeating, which lead to increased expression of C/EBP, contribute to the regulation of pancreatic -cell mass

EPR (electron paramagnetic resonance) spectroscopy experiments have demonstrated that peroxynitrite oxidizes BH4 to the (non-protonated) BH3 (trihydrobiopterin) radical, and then to BH2, with a rate constant estimated to be 6 10 3 M 1 s 1 , several-fold higher than reactions between peroxynitrite and ascorbate, glutathione or thiol groups [68]

mSystems 6:e00443-21

1971;125:117P

Nitrogen gas was passed through the vials, and volatile aromatic compounds were trapped on an adsorbent cartridge connected through the septum