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USA 112 , 63776382 (2015)

In animal models of ICH and ischemic stroke, 5-lipoxygenase has been demonstrated to induce ferroptosis induction critically

Solasonine induced iron overload, mitochondrial injury, and the destruction of the glutathione redox system by inhibiting the expression of GPX4 and SLC7A11 in lung adenocarcinoma cells (Zeng et al., 2022)

A recent editorial underscores that ferroptosis, driven by oxidative stress, mitochondrial dysfunction, and immune dysregulation, is a key mechanistic node in PD and Alzheimers disease (AD), highlighting its potential as both a biomarker and a therapeutic target (Dar et al., 2024)

Herpes simplex virus type 1 infection of the central nervous system: insights into proposed interrelationships with neurodegenerative disorders

In some cases, activity and M pro modifications were determined by first stopping the assay at a set time by acidification with formic acid (FA)/trifluoroacetic acid (TFA) and then analyzed by RP-HPLC using a 2% acetonitrile gradient on a Vydac C18 column as described below