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Suppression of Cytokine Production and Inhibition of NF-B and iNOS Activities NAC has been shown to attenuate neuroinflammation by downregulating key pro-inflammatory mediators and signaling pathways, particularly cytokines, NF-B, and inducible nitric oxide synthase (iNOS) [9,10,11,51,52]

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Evidence from a systematic review and meta-analysis: classical impaired glucose tolerance should be divided into subgroups of isolated impaired glucose tolerance and impaired glucose tolerance combined with impaired fasting glucose, according to the risk of progression to diabetes