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However, urine output is not a very reliable index in patients who are taking medication or are perioperative, and other commonly used surrogate indices, such as the serum creatinine concentration, creatinine clearance, or GFR, can only show that AKI and functional impairment is already present, rather than being predictors of their development at an early stage (113)

Its stability, versatility, and broad pathway engagement make it valuable for ongoing mechanistic research across multiple biological systems

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BPC-157 is studied for supporting repair signaling and protecting tissues under stress, including effects on blood vessel function and inflammatory mediators in preclinical research

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