Rosendahl AH, Hietala M, Henningson M, Olsson H, Jernstrm H
Prevention of brain hypoperfusion-induced neurodegeneration in rats hippocampus by black cumin fixed oil treatment
Abbreviations ADFI: Average daily feed intake ADG: Average daily gain AGP: Antibiotic growth promoters BWG: Body weight growth CAT: Catalase CP: Crude protein DM: Dry matter E.coli : Escherichia coli EE: Ether extracts ERK: Extracellular signal-regulated kinases G:F : Gain to feed ratio GE: Gross energy GIT: Gastrointestinal tract GnRH: Gonadotropin-releasing hormone GSH-Px: Glutathione peroxidase IgA: Immunoglobulin A IGF-1: Insulin-like growth factor 1 IgG: Immunoglobulin G IgM: Immunoglobulin M IL-1: Interleukin 1 IL-10: Interleukin 10 IL-12: Interleukin 12 IL-1: Interleukin 1 IL-2: Interleukin 2 IL-6: Interleukin 6 INF-: Interferon-gamma JNK: C-Jun N-terminal kinases MAPK: Mitogen-activated protein kinase MCP-1: Monocyte chemotactic protein-1 MDA: Malondialdehyde MyHC: Myosin heavy chain NF-kB: Nuclear factor kappa-light-chain-enhancer of activated B cells NO: Nitric acid Nrf2: Nuclear factor erythropoietin-2-related factor OM: Organic matter SCFA: Short-chain fatty acids SIgA: Secretory immunoglobulin A SOD: Superoxide dismutase T-AOC: Total antioxidant capacity TBARS: Thiobarbituric acid reactive substances TGF-1: Transforming growth factor- TLR: Toll-like receptors TNF- : Tumor necrosis factor TNF-: Tumor necrosis factor TNF-: Tumor necrosis factor ZO-1 : Zonula occludens-1 References Abdelli N, Sol-Oriol D, Prez JF (2021) Phytogenic feed additives in poultry: achievements, prospective and challenges
The highly mutagenic and carcinogenic 10 S (+)- trans -BP- N 2 -dG adduct is the predominant steroisomer found in human cells treated with BP (~ 90%) 13 , and is more resistant to removal by the nucleotide excision repair (NER) pathway than the (+)- cis- adducts and ()- cis- adducts 14, 15
Additionally, GHK demonstrated the ability to reverse the expression of various genes, most notably, the gene signature of COPD
Do not try any new medication without consulting your healthcare provider
