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Direct targeting of SLC7A11 includes the use of inhibitors: sulfasalazine (128, 129), erastin (130, 131), imidazole ketone erastin (IKE) (132), sorafenib (133, 134), and HG106 (78)

This deficiency can cause health issues such as anemia, fatigue, and a lack of focus

Modulating the gut microbiome and restoring gut barrier integrity are key therapeutic avenues, and several microbiome-targeted strategies have been explored [19,78,79]

In contrast, [email protected] demonstrated delayed-onset penetration kinetics, achieving maximal epidermal accumulation at 6 h post-administration with limited dermal distribution and negligible subcutaneous deposition

Synthesis and screening of novel vitamin E derivatives for anticancer functions