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Along with decreased visceral adiposity and adipocyte size, these rats also had higher levels of hepatic carnitine palmitoyl-transferase I (CPT-1), a crucial enzyme that controls long-chain fatty acid oxidation and lowers circulating TAG levels (Thompson et al., 2017)

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Severe Cases: Severe cases can cause deep cracks that may bleed, although this is uncommon in angular cheilitis

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doi: 10.3748/wjg.v28.i12.1187 51 SongYLiuXChengWLiHZhangD

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Even though there are concerns for the development of kidney disease in CPTII patients due to the high metabolic overload associated to rhabdomyolysis, end-stage chronic renal insufficiency requiring dialysis is only occasionally reported in these patients (Joshi and Zierz, 2020)

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