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doi: 10.3390/antiox10091442 118

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J Pathol 201 : 119126 Burgess T, Coxon A, Meyer S, Sun J, Rex K, Tsuruda T, Chen Q, Ho SY, Li L, Kaufman S, McDorman K, Cattley RC, Sun J, Elliott G, Zhang K, Feng X, Jia XC, Green L, Radinsky R, Kendall R (2006) Fully human monoclonal antibodies to hepatocyte growth factor with therapeutic potential against hepatocyte growth factor/c-Met-dependent human tumors

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At the AACR 2026, a poster presented by Crown Bioscience demonstrated how genOways hSA/hFcRn mice (genO-hSA/hFcRn), enable a predictive, humanrelevant PK assessment of ADCs across diverse linker and payload formats, showing how this model could be an alternative to replace the use of non-human primates (NHPs)

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Circ_0000745 interference has also been shown to inhibit the cell cycle and glycolysis and increase the levels of intracellular iron and lipid ROS induced by erastin, thus accelerating ferroptosis (Yang et al., 2022)

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