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Likewise, results obtained in various diet-induced MASLD/MASH rodent models revealed a marked reduction in CAT activity in the serum as well as the liver of these animals as compared to respective controls (Dai et al

The role of membrane proteolysis, particularly through pathways such as ERAD and intramembrane proteolysis, is crucial for cardiovascular health

Multi-pronged approach The central message is coordination of care

626,627,628 Experimental evidence is accumulating that astrocytes readily respond to lifestyle modifications, and may be instrumental in conferring clinical benefits

334 Beyond degradation failure, autophagy-lysosomal dysfunction contributes to the pathological propagation of aggregation-prone proteins