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Thus, residues Tyr110 and Lys105 might share a function in accordance with the glutathione activator model but might also differ, for example, regarding the protonation state of the active site cysteine residue

NAFLD is estimated to progress to a more severe condition called nonalcoholic steatohepatitis (NASH) in about one-third of NAFLD patients, as well as to increase the risk of cirrhosis and liver cancer (13)

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1 H NMR (DMSO 600 MHz): 2.38 (s, 9H), 7.74 (s, 6H) 8.55 (s, 3H) 13.14 (s, 3H) ESI-MS (negative ionization mode): ESI-MS negative ionization mode: [M + H] + calcualted m/z = 496.17 found m/z = 496.17

Springer Link , Biochimica Et Biophysica Acta , vol

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