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Data analysed by two-way repeated measures ANOVA to assess main effects of treatment ( b , c , f , g , i and j )

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However, while FEV 1 is the primary endpoint in most clinical trials of mucus-targeted therapies, it is insensitive to early or small airway mucus obstruction [48] and correlates poorly with mucus plug burden on imaging [11]

We observed a similar pattern in GAPDH-deficient cells indicating that ATP depletion does not affect the gross morphology of the actin cytoskeleton

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10.1007/s10753-023-01825-2 94