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The depletion of GSH levels is considered the main feature in cell damage

Proc Natl Acad Sci 89:444448 Kolesnik B, Palten K, Schrammel A, Stessel H, Schmidt K, Mayer B, Gorren AC (2013) Efficient nitrosation of glutathione by nitric oxide

Backhaus, M

Emerging green nanotechnologies even explore edible nanocarriers that come from food itself- for instance, plant-derived exosome-like vesicles have been proposed as natural nanocapsules for dietary bioactives, offering innate biocompatibility and low immunogenicity (239241)

Some of the most commonly mutated genes in familial cases of PD, including LRRK2 and GBA1 , have key functions in regulating lysosomal health [126,127,128] and both are highly expressed in immune cells [9, 129, 130]