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It is increasingly apparent that an integrative examination of the molecular underpinnings of cell death is imperative for advancing the field, particularly within the framework of inter-pathway functional synergy

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Rare serious risks include polycythemia (in those with baseline elevated red blood cell counts) or hypokalemia during rapid B12 repletion

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Pembrolizumab plus lenvatinib was associated with the highest incidence of high-grade AEs, whereas nivolumab plus ipilimumab showed the lowest