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However, emerging drugs that target the main autoantigen (monoclonal antibodies, small molecules, peptides) or block the immune pathway have been recently tested in clinical trials

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Importantly, this death mechanism differs from apoptosis, necroptosis and ferroptosis, as evidenced by insensitivity to their inhibitors and absence of classical markers like caspase-3 cleavage, cystine crystal formation or ATP depletion (Liu X

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