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As a master antioxidant, Glutathione protects cells from damage caused by free radicals and reactive oxygen species, which are implicated in various chronic diseases

While invasive methods are not currently considered clinically practical for the assessment of airway remodeling in asthma and obesity, non-invasive approaches such as the evaluation of CT scans and biomarkers are emerging as potential tools for predicting airway remodeling in these conditions

Metformin, an AMP-activated protein kinase (AMPK) activator widely used in diabetes, is currently in phase I clinical trials for heart failure with preserved ejection fraction (HFpEF) (Tables 1 and 2)