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Environmental and occupational exposures represent another significant indication for AOX therapy

Int J Food Sci Nutr 70(5):603611 Fu Y-F, Zhu Y-N, Ni J, Zhong X-G, Tang W, Re Y-D et al (2006) A reversible S-adenosyl-L-homocysteine hydrolase inhibitor ameliorates experimental autoimmune encephalomyelitis by inhibiting T cell activation

Dosages typically range from 100 to 500 mg per day

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Experimental investigations have reported interactions with VEGFR2 phosphorylation, focal adhesion kinase (FAK) activation, ERK1/2 signaling, nitric oxide-associated pathways, and extracellular matrix regulatory networks

doi: 10.1084/jem.20111627 91 TamburiniBABurchillMAKedlRM