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Oxidative stress and motor neurone disease

10.1002/adma.202413779 65 HwangY.-H.ShepherdS

Mustachio, L

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Atherosclerosis progression, as a chronic inflammatory mechanism, is characterized by immune system dysregulation associated with increased pro-inflammatory cytokine production, including interleukin 6 (IL-6), tumor necrosis factor- (TNF-), and IL-1, as well as pattern recognition receptor proteins like CRP (170, 261267)

In addition, some evidence showed that OSF patients have cytogenetic damage, manifested by elevated indicators such as sister chromatid exchange rates, 48,49 micronucleus cell numbers 50,51 and degree of DNA damage, 52 which can be attributed to the genotoxic effects of AN chewing