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While enzymes such as glutathione peroxidase 4 (GPx4) typically utilize cellular glutathione (GSH) stores to scavenge lipid hydroperoxides and prevent LPO-induced damage, erastin-mediated inhibition of cysteine uptake through the Xc- transporter compromises this defense strategy, leading to cell death

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Description A neuropeptide that when infused into the mesodiencephalic ventricle of recipient rabbits induces spindle and delta EEG activity and reduced motor activities SEQUENCE: H-Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu-OH (trifluoroacetate salt) ONE-LETTER SEQUENCE: WAGGDASGE MOLECULAR FORMULA: C 35 H 48 N 10 O 15 MOLECULAR WEIGHT: 848.82 STORAGE CONDITIONS: -20 5 C CAS REGISTRY NUMBER: [62568-57-4] SYNONYMS: RESEARCH AREA: Neuropeptides REFERENCES: G.A.Schoenenberger and M.Monnier, Proc

10.18632/oncotarget.14270 63

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Codon 877 mutation in the androgen receptor gene in advanced prostate cancer: relation to antiandrogen withdrawal syndrome