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Hare DL, Toukhsati SR, Johansson P, Jaarsma T

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All participants were informed about the study design and then written informed consent was obtained from all volunteers

Case 2, The 47-year-old in perimenopause Estrogen decline had accelerated her concern profile in a way nobody had warned her about, and she felt blindsided by how quickly her skin and her overall presentation had shifted in eighteen months