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"We know these blood vessels are vulnerable to damage at exposure to an incredibly low numbers of cigarettes," he said

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Upon exposure to nicotine, the release of granulocyte-macrophage colony-stimulating factor (GM-CSF) and the activation of Akt are also stimulated in airway epithelial cells (AECs) [93, 94]

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[33] However, it never had its own buildings or staff, nor regular funding, [16] and overall its research into the dangers of tobacco was limited, and only of marginal scientific significance and repute