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The subsequent round of DNA replication is, therefore, associated with the loss of DNA methylation markers [135,136,137]

These reactive oxygen species may subsequently interact with superoxide dismutase and glutathione, leading to reduced levels of these antioxidants, making the brains ability to cope with oxidative stress damage much reduced and further accelerating neuronal cell damage in the corresponding brain regions ( The glutamate hypothesis of schizophrenia suggests that the function of N-methyl-D-aspartate (NMDA) receptors is impaired in this disorder

They are signaling molecules, neurotransmitters, infection-fighters, and growth factors that promote tissue repair and healing

doi: 10.1016/j.cell.2023.02.002

These may feel more intense with IR because the medication reaches peak levels in the bloodstream faster

References Saha, S., Chant, D., Welham, J