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Targeted treatment to mitophagy-mediated neuronal pyroptosis Anesthesia and surgery can lead to insufficient PINK1-mediated mitophagy, which in turn activates the caspase-3/GSDME pyroptosis signaling axis, ultimately resulting in postoperative cognitive dysfunction (POCD)

Sfanos KS, Yegnasubramanian S, Nelson WG, De Marzo AM

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This can potentially help to protect and repair nerve tissue after injuries

On the basis of the evidence presented above, the major objectives of the present study were (1) to determine the effects of GSHee on ventilatory performance in freely-moving adult rats, and (2) to determine whether the prior administration of GSHee is able to ameliorate the negative effects of fentanyl on breathing and gas-exchange in freely-moving adult rats

With intramuscular (IM) shots, you get fast, effective results your body can truly use