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Drug Discov Today 20:122128

GHD is much worse in children who received radiation for brain tumors than for the other tumors (Murray et al., 1999

In practice, that same additive quality is also the main risk: two strong satiety agents together can suppress appetite and slow the gut more than intended, which is why tolerability not maximum weight effect tends to be the limiting factor in any amylin-plus-incretin discussion