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Despite longer duration of treatment, no significant weight loss was observed

Therefore, only low-intensity aerobic training (60% VO 2 max, 2030 min, 23 sessions/wk) should be applied, while high-intensity exercise should be avoided

It should be noted that this is an in vitro / ex vivo study, and therefore, some of the confounding influences of TMAO may be missing in these ex vivo models, such as the influence of TMAO on the vasculature, endothelial responses, and the immune system

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PLoS ONE 8 , e74341 (2013)