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Description

mTOR and HDAC Inhibitors Converge on the TXNIP/Thioredoxin Pathway to Cause Catastrophic Oxidative Stress and Regression of RAS-Driven Tumors

None of the products sold are intended for human or animal use, consumption, administration, or application of any kind

BSR20181226

These diverse actions underscore the importance of ChaC2 in maintaining cellular redox homeostasis and antioxidation mechanisms

It is currently in phase IIb trial aiming at recruiting 185 patients (NCT02665364)

doi: 10.1093/brain/awz190 Summary Keywords multiple sclerosis, EBV, vitamin D, immune system, molecular mimicry Citation Rasheed A and Khan G (2024) Epstein-Barr virus, vitamin D and the immune response: connections with consequences for multiple sclerosis