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This is the third indication for Tremfya, which is also approved to treat moderate-to-severe plaque psoriasis and psoriatic arthritis

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10.1155/2012/736837 46 LushchakV

Additionally, we found that the His-tag affects the entropy and enthalpy of the first SAM binding event in ITC in comparison to the constructs without a His-tag (Supplementary Figs