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Xiu-Ying et al., 2021)

Because HCAs are mutagenic and possible human carcinogens contributing to the increased risk of colorectal cancer from eating meat, a detailed understanding of their physiological transformation pathways is a critical component of risk analysis 27,28,29,30

In vivo , 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced PD mice exhibited a marked reduction in tyrosine hydroxylase (TH)-positive neurons and CD31 expression, along with significant decreases in GSH and GPX4 levels

10.1021/mp500542a 157 NingW.WangS.DongX.LiuD.FuL.JinR.et al (2015)

However, he did not achieve sustained virologic response (SVR) and was subsequently treated with ursodeoxycholic acid at a local clinic

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