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Some of these inflammatory mediators act on the vascular musculature to promote vasodilation, which increases blood flow and capillary permeability, to allow for the influx of leukocytes (Leick et al

10.1093/jnci/94.12.926 J

Single cell transcriptomics identifies a signaling network coordinating endoderm and mesoderm diversification during foregut organogenesis

Here, we describe a novel kinetic assay to measure NADPH consumption rate by GSR in the cytosol and the mitochondria (Fig 1A)

This leads to local ischemia, hypoxia, reduced pH, and decreased temperature, all of which lower uric acid solubility and impair urate excretion