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Surgical Therapy

doi: 10.1038/nchembio.2239 71 DixonSJWinterGEMusaviLSLeeEDSnijderBRebsamenMet al

3.3.2 4-hydroxy-2-nonenal 4-hydroxy-2-nonenal (4-HNE) is a lipid peroxide produced by polyunsaturated fatty acids (PUFAs) in response to oxidative stress (Figure 3)