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However, continuous treatment to reestablish the p53 functions could result in pharmacological resistance, since the increase in antioxidant activity in cancer cells would prevent cell death caused by exogenous stress generated by radiotherapy or the oxidant stress of a chemotherapeutical treatment (Conklin, 2004

There is no functional difference between the two

Back in 2005, it affected roughly 2% of the U.S

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SL.Hazen et al Published December 10, 2018 J Clin Invest 2018

A history of other substance use, higher socioeconomic status, or exposure to family violence or substance abuse has also been reported more often in this population (37, 38)