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The limitations of existing research are reflected in several key aspects: (1) Lack of clinical research: Most studies investigating the antiaging effects of PCs rely on in vitro cell culture or in vivo animal models

This age-related decline in immune function, called immune senescence, leads to alterations in the cytokine microenvironment as well as impaired innate and adaptive immunity and is closely related to oxidative stress (149)

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These agents generally induce either permanent DNA damage or temporary inactivation of DNA ( 5.4.2 Induction of ROS generation In recent years, several biomaterials have been synthesized that exhibit both anticancer and antibacterial activities

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