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Unprotected sex, especially with new or multiple partners A man who has sex with men HIV-positive (syphilis and HIV often occur together) A history of other STIs, which can increase susceptibility Sex worker or a partner who does sex work Drugs that impair judgment, which can increase risky sexual behavior Sexually active with more than one partner

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2A), 7/10 patients had a higher score of H3K27me3 (Fig

Avoid concomitant use of opiate antitussives