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In fact, circulating MOTS-c levels are shown to increase with exercise and, much like GHK-Cu and other endogenous peptides, natural levels of MOTS-c tend to decrease with age, and for this reason it has gained interest in the field of aging research

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Eight weeks post-vaccination, a decrease in number and size of atherosclerotic plaques was reported, along with a decrease of GPNMB senescent cells number

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