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Studies have found that women taking birth control that contains estrogen tend to have higher vitamin D levels than those who dont, and the effect of vitamin D supplements is improved for those on birth control [31]

This is why, at the beginning of the 20th century, when it was discovered that eating liver improved patients with pernicious anemia, they had to eat huge amounts to achieve a pharmacological effect. In these cases, we find an approximate absorption of, with luck, between 1-2% of the dose administered, but it is not uncommon for it to be even lower (0.5%) depending on the size of the dose, previous reserves, and other factors and individual conditions of each subject

see Allen et al (2018) for more details

The mechanism of gastric bypass surgery is to cause restriction by creating a smaller stomach pouch and then causing nutrient malabsorption by bypassing a portion of the stomach and small intestine

are currently or previously employed by Amgen, Inc